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Study Finds Earth Located in the Lamest Fucking Part of Universe

Citing factors ranging from the dumb, ugly asteroid belt separating the terrestrial planets from the gas giants, to the super-boring and practically empty interstellar medium extending in nearly every direction, new research published Wednesday by the International Astronomical Union has concluded that Earth is located in "by far the lamest" region of the observable universe.

From The Onion


The Psychedelic Experience

What is the psychedelic experience? Aldous Huxley believed it was the fundamental craving of the human spirit. A desire to turn off the survival biased filter of perception just for a moment... and catch a glimpse beyond the bars of our cognitive prison.

From WarriorPoetUS


Do Smart Students Smoke More Pot?

It seems like everyone knows someone who is incredibly smart, but also smokes a lot of pot! Is there a link between someone's intelligence and their likelihood to smoke marijuana? Trace was curious and did some digging of his own to find out.


Sneak Alcohol onto a Cruise.

This video will show you how to put hard alcohol into the wine bottle without using a cork opener. Good for sneaking it on cruise ships that allow you to bring wine but not hard alcohol.


How Drugs and Alcohol Affect your Brain

You know that drugs and alcohol affect you, but how do they actually make your body change?

In this video we talk a bit about how drugs and booze affect your brain, and if you join us next time we'll go even further into how these substances affect your mood and overall health.

If you're interested, here are some good places to learn more:

*The first neurotransmitter we reference is called GABA- it's responsible for regulating neuron excitation http://en.wikipedia.org/wiki/Gamma-Aminobutyric_acid
*When we reference neurotransmitters that control memory and learning, we are talking about the NMDA system http://en.wikipedia.org/wiki/NMDA_receptor
*Two more good resources can be found below
http://en.wikipedia.org/wiki/Neuropharmacology
http://www.straightdope.com/columns/read/2648/still-smokin-what-are-the-long-term-effects-of-marijuana

So spread the word! (And be sure to subscribe for more Things You Should Know)

-Team TYSK

Features the song "Wickenden Kids" by the Rare Occasions - http://therareoccasions.bandcamp.com/

Citations (enable annotations to view):
Crews, Fulton T., and Kim Nixon. "Mechanisms of neurodegeneration and regeneration in alcoholism." Alcohol and Alcoholism 44.2 (2009): 115-127.

Di Marzo, Vincenzo, et al. "Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action." Trends in neurosciences 21.12 (1998): 521-528.

Katona, István, et al. "Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons." The Journal of neuroscience 19.11 (1999): 4544-4558.

Lovinger, David M., Geoffry White, and Forrest F. Weight. "Ethanol inhibits NMDA-activated ion current in hippocampal neurons." Science 243.4899 (1989): 1721-1724.

McBride, Wl J., et al. "Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats." Alcohol 7.3 (1990): 199-205.

Meier, Madeline H., et al. "Persistent cannabis users show neuropsychological decline from childhood to midlife." Proceedings of the National Academy of Sciences 109.40 (2012): E2657-E2664.


A Guy Walks into a Bar

After an awkward exchange, two strangers realise that picking up a member of the opposite sex can be a tricky business.

From Rhys Wakefield